July 13, 2025 Breaking News, Latest News, and Videos

Breaking Neuroscience Ground: Daniel F. Kelly M.D. and the Pacific Neuroscience Institute Lead in Comprehensive Treatment Neurological Conditions

 By Staff Writer

 

Santa Monica’s hip and laid-back community is home to some very high tech neurological medical experts. Daniel F. Kelly, MD, director of Pacific Neuroscience Institute, is considered to be among the top neurosurgeons in the US, well known for his use of minimally invasive “keyhole” endoscopic brain and pituitary surgical techniques.

As director of Pacific Neuroscience Institute, Dr. Kelly collaborates with a multidisciplary team of specialists at PNI, John Wayne Cancer Institute, Providence Saint John’s Health Center, and other Providence Southern California affiliates to ensure patients get customized treatment for their specific condition.

Dr. Kelly came to the Providence Saint John’s Health Center in 2007, following 14 years at UCLA. In practice now for over 23 years Dr. Kelly’s unique blend of surgical expertise and ability to put patients immediately at ease, has earned him Southern California’s SuperDoctors award 11 years in a row, and multiple TopDoctor and Patient’s Choice awards.

In 2015, Dr. Kelly and his three co-founders Drs. Chester F. Griffiths (ENT – Otolaryngology), Santosh Kesari (Neuro-Oncology) and Howard R. Krauss (Neuro-Ophthalmology), established the Pacific Neuroscience Institute which is a multidisciplinary institute devoted to the care of patients with a wide spectrum of neurological and cranial disorders. Doctors at PNI’s Centers of Excellence see and treat local, nationwide and international patients.

“PNI’s roots are in the brain tumor and pituitary disorders program which we began at Saint John’s in 2007,” said Dr. Kelly. “Pituitary disorders cover a wide range of diseases with such diverse symptoms; patients often spend years trying to get a correct diagnosis.” Pituitary adenomas are the most common benign tumor occurring in the pituitary gland. This small yet mighty gland regulates a wide array of bodily functions including growth and development, sexual and reproductive functions, body metabolism and stress response and in fact is a key player in cognitive function and overall brain health.

The great majority of symptomatic pituitary adenomas are now removed via the natural corridors of the nostrils with a team surgery approach using a high-definition endoscope as the visualization tool. “The beautiful panoramic endoscopic view allows us to sneak in and out of the midline skull base and brain area without brain retraction and without visible scars on the face or head”, Dr. Kelly said. “We also apply the same endoscopic ‘keyhole’ philosophy of minimally invasive yet maximally effective approaches for both benign brain tumors such as meningiomas, and malignant tumors such as metastatic brain tumors and glioblastomas (GBM). Using surgical navigation, ultrasound and low-profile instrumentation, many patients can have a brain tumor removed through one of several keyhole access points such as via a small eyebrow incision, from behind the ear or using ‘gravity assisted’ procedures to reach the tumor without traversing normal brain,” he added.

PNI began with the Brain Tumor and Pituitary Disorders Centers and rapidly integrated other specialities including centers for eye, ear & skull base, facial pain, adult hydrocephalus, movement disorders, strokes and aneurysms and neuroscience research which spearheads PNI’s clinical trials. Current clinical trials led by neuro-onocologist Dr. Kesari, include a large number of glioblastoma and metastatic brain cancer studies. In addition, recent neurosurgical clinical trials led by neurosurgeon Dr. Achal Singh Achrol have used modified adult stem cells to treat motor deficits due to brain trauma or stroke.

Knowledge and education are a priority at PNI and young doctors, international scholars and interns are trained in a setting that provides both academic and practical neuroscience experience, including a hands-on neuroanatomy dissection laboratory directed by neurosurgeon Dr. Garni Barkhoudarian.

PNI and JWCI physicians and scientists have a long academic track record with many hundreds of peer-reviewed neuroscience and neuro-oncology publications. “We are continually striving to innovate and improve our treatments with the goal of helping patients live longer, while maintaining their quality of life. By publishing our findings, we hopefully will help change the global standard of care,” said Dr. Kelly.

On March 19, 2018, PNI opened its newly renovated historic clinic building, a Santa Monica Landmark building. Patients can visit the new clinic located on the corner of 22nd Street and Arizona Avenue, in the center of the Santa Monica community, and just across the street from the Providence Saint John’s E.R. A grand opening event is slated for May.

“We’re excited that Pacific Neuroscience Institute is part of Santa Monica. Long-time residents know the 2125 Arizona building. It’s a beautiful restoration and now again a medical clinic as it was back in the 1950’s. We think patients will appreciate the esthetics as well as the continued high-level of care they receive,” said Dr. Kelly.

For more information about PNI, visit pacificneuro.org.

Dr. Daniel F. Kelly, M.D.
Photo: Pacific Neuroscience Institute
<>Related Posts

County Health Leaders Decry Federal Policy Barring Undocumented from Programs

July 12, 2025

July 12, 2025

The officials argued the policy jeopardizes care for all residents, noting it could deter people—regardless of status—from seeking treatment  Leaders...

County Supervisors Move to Preserve Measure J Amid Charter Error

July 12, 2025

July 12, 2025

Measure J mandates that at least 10% of the county’s locally generated, unrestricted funds be allocated to community investments like...

LA Medical Center Seeks Help Identifying Unconscious Patient

July 12, 2025

July 12, 2025

He has been unconscious since admission, and staff have been unable to determine his identity Los Angeles General Medical Center,...

Mayor Bass Issues Directive to Protect Immigrant Communities

July 12, 2025

July 12, 2025

The order expands access to city resources for affected families and requests records from ICE, including details on arrests Mayor...

Downtown Santa Monica CEO Andrew Thomas to Step Down

July 11, 2025

July 11, 2025

Thomas, who rejoined DTSM, Inc. in 2022, oversaw the introduction of a private security program, expanded homeless outreach, and boosted...

Conservancy to Tour Historic Miles Playhouse at State of the City Event

July 11, 2025

July 11, 2025

Built in 1929, the Miles Playhouse serves as the centerpiece of Lincoln Park The Santa Monica Conservancy will offer 15-minute...

Sen. Ben Allen Highlights Challenges, Economic Gains for LA28 Olympics

July 11, 2025

July 11, 2025

The remarks came during the first informational hearing of the Senate’s Special Committee on International Sporting Events State Sen. Ben...

(Video) Summer Camp at School of Rock West LA Turns Kids Into Rockstars

July 11, 2025

July 11, 2025

To Sign Up Now, Go To Schoolofrock.com Summer Camp at School of Rock West LA Turns Kids Into Rockstars To...

L.A. Louver Marks David Hockney’s 88th with Exhibit

July 11, 2025

July 11, 2025

Hockney, a British artist born in 1937, gained fame with the British Pop Art movement and later became known for...

Suspect Arrested in Shoe Retail Theft Spree Across LA County

July 11, 2025

July 11, 2025

During the search, police recovered two firearms and a significant quantity of merchandise The Los Angeles Police Department’s Organized Retail...

Suspect Arrested in Santa Monica Pier Arson Incidents

July 10, 2025

July 10, 2025

The suspect, matching video footage from an arcade, was taken into custody Santa Monica Police Department officers arrested a suspect...

SMPD Launch New Recruitment Website Amid High Vacancy Rates

July 10, 2025

July 10, 2025

The site features multimedia content, including day-in-the-life videos and officer profiles, highlighting the impact of serving the community The Santa...

Father-Daughter Authors to Host Book Signing to Aid Fire-Affected Women

July 10, 2025

July 10, 2025

Ten percent of proceeds from book and art sales will benefit the Pacific Palisades Rebuilding Fund, a nonprofit initiative created...

Metro Reports Crime Drop, Higher Rider Satisfaction, and Progress on Major Projects

July 9, 2025

July 9, 2025

The Authority said the drop in violent incidents—down to the lowest level since May 2019—coincided with more uniformed personnel and...

Santa Monica Joins Regional Lawsuit to Halt Unconstitutional ICE Raids

July 9, 2025

July 9, 2025

The motion to intervene seeks to ensure that Santa Monica and other plaintiff-intervenors can advocate for their residents’ rights in...